Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GPR4 | P46093 | 3/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468521 | 0.90 | AGTR1 (0.33) | — | |
| SCHEMBL9706632 | 0.89 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL9468567 | 0.89 | PTGDR2 (0.37) | PTGDR2ACHE | |
| SCHEMBL9468626 | 0.88 | PTGDR2 (0.33) | PTGDR2ACHE | |
| SCHEMBL9468043 | 0.85 | PTGDR2 (0.36) | PTGDR2 | |
| SCHEMBL9706628 | 0.79 | AGTR1 (0.38) | PTGDR2 | |
| SCHEMBL9467181 | 0.79 | AGTR1 (0.39) | — | |
| SCHEMBL9468519 | 0.79 | PTGDR2 (0.36) | PTGDR2 | |
| SCHEMBL9468571 | 0.78 | — | — | |
| SCHEMBL9706707 | 0.77 | PTGDR2 (0.42) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |