Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706628 | 0.89 | AGTR1 (0.38) | PTGDR2AGTR1 | |
| SCHEMBL9468523 | 0.89 | PTGDR2 (0.33) | PTGDR2 | |
| SCHEMBL9706707 | 0.87 | PTGDR2 (0.42) | PTGDR2AGTR1AGTR2 | |
| SCHEMBL9468179 | 0.87 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL9468521 | 0.79 | AGTR1 (0.33) | AGTR1 | |
| SCHEMBL9468065 | 0.78 | AGTR1 (0.43) | PTGDR2AGTR1 | |
| SCHEMBL9468567 | 0.77 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL9706701 | 0.77 | PTGDR2 (0.41) | PTGDR2AGTR1 | |
| SCHEMBL9468626 | 0.76 | PTGDR2 (0.33) | PTGDR2 | |
| SCHEMBL9468043 | 0.76 | PTGDR2 (0.36) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |