Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CASP1 | P29466 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | CASP7 | P55210 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 9/20 | 0.56 |
| ▸ | CA2 | P00918 | 9/20 | 0.56 |
| ▸ | CA9 | Q16790 | 9/20 | 0.56 |
| ▸ | CA12 | O43570 | 7/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995319 | 0.88 | CASP1 (0.86) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL14302915 | 0.87 | TSHR (0.52) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL9566650 | 0.86 | CASP1 (0.83) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL4781427 | 0.81 | ALDH1A1 (1.00) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL14354608 | 0.81 | CA1 (0.48) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL9632412 | 0.81 | ESR1 (0.75) | CA1CA2CA9CA12SCN2A | |
| SCHEMBL14260441 | 0.81 | CA9 (0.78) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL12912937 | 0.81 | CA9 (0.78) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL17187966 | 0.81 | CA1 (0.56) | TSHRNPC1ALDH1A1CASP1RAB9A | |
| SCHEMBL12731757 | 0.80 | CA1 (0.47) | TSHRNPC1ALDH1A1CASP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212277-A | Engineering plastics | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-05-18 | — | — | US | disclosed |