Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468728 | 1.00 | CYP2D6 (0.47) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL22329028 | 0.81 | CYP2D6 (0.46) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL10755241 | 0.81 | CYP2D6 (0.46) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL25606235 | 0.78 | CYP2D6 (0.44) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL9743805 | 0.78 | CYP2D6 (0.44) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL29253119 | 0.78 | CYP2D6 (0.44) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL9743811 | 0.78 | CYP2D6 (0.44) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL25606084 | 0.78 | CYP2D6 (0.44) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL2915798 | 0.77 | ALDH1A1 (0.42) | CYP2D6CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL2304908 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208260-A | Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder | G. D. SEARLE & CO. (US) | 1993-05-04 | — | — | US | disclosed |