Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468237 | 0.89 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9468578 | 0.89 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL9468510 | 0.87 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9468570 | 0.86 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9468604 | 0.84 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9468532 | 0.84 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9248395 | 0.84 | — | — | |
| SCHEMBL9530791 | 0.79 | — | — | |
| SCHEMBL9468672 | 0.78 | — | — | |
| SCHEMBL9309645 | 0.78 | AGTR1 (0.63) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |