⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474267 | 0.92 | — | — | |
| SCHEMBL9468245 | 0.89 | — | — | |
| SCHEMBL9468581 | 0.88 | — | — | |
| SCHEMBL9248395 | 0.80 | — | — | |
| SCHEMBL9309653 | 0.79 | AGTR1 (0.38) | — | |
| SCHEMBL9480825 | 0.78 | PTGER1 (0.42) | — | |
| SCHEMBL9468670 | 0.78 | AGTR1 (0.48) | — | |
| SCHEMBL9309051 | 0.78 | AGTR1 (0.39) | — | |
| SCHEMBL9309325 | 0.77 | AGTR1 (0.38) | — | |
| SCHEMBL9309706 | 0.77 | AGTR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |