Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.64 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.62 |
| ▸ | FASN | P49327 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809735 | 0.88 | ATM (0.67) | MAPK1HSD17B1HSD17B2SRD5A2ATM | |
| SCHEMBL11392123 | 0.86 | TSHR (0.61) | HSD17B1HSD17B2CLK1DYRK1ADYRK1B | |
| SCHEMBL189236 | 0.86 | CLK1 (0.75) | MAPK1HSD17B1HSD17B2CLK1DYRK1A | |
| SCHEMBL27735439 | 0.86 | CLK1 (0.75) | MAPK1HSD17B1HSD17B2CLK1DYRK1A | |
| SCHEMBL809540 | 0.85 | FASN (0.76) | HSD17B1HSD17B2CLK1DYRK1ADYRK1B | |
| SCHEMBL29699163 | 0.85 | FASN (0.76) | HSD17B1HSD17B2CLK1DYRK1ADYRK1B | |
| SCHEMBL3177794 | 0.84 | PARP1 (0.59) | MAPK1SRD5A2ATMTDP1L3MBTL1 | |
| SCHEMBL144795 | 0.84 | ATM (0.74) | HSD17B1HSD17B2CLK1DYRK1ADYRK1B | |
| SCHEMBL22717015 | 0.82 | MEN1 (0.70) | HSD17B1HSD17B2CLK1DYRK1ADYRK1B | |
| SCHEMBL9229699 | 0.82 | CA12 (0.73) | HSD17B1HSD17B2CLK1DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013116605-A1 | COMPOSITIONS FOR THE TREATMENT OF TUBERCULOSIS AND METHODS OF USING SAME | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | WO | disclosed |
| US-5264538-A | Cyclic poly(aryl ether) oligomers | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5264520-A | Polymerization of cyclic poly(aryl ether) oligomers | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0413257-A2 | Cyclic poly(aryl ether) oligomers, a process for preparation thereof, and polymerization of cyclic poly (aryl ether) oligomers | THE DOW CHEMICAL COMPANY (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4287209-A | USEFUL AS METABOLIC REGULATORS, AND HERBICIDES | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1981-09-01 | — | — | US | disclosed |
| US-4146385-A | METABOLIC REGULATORS, CARDIOVASCULAR AGENTS, HERBICIDES | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1979-03-27 | — | — | US | disclosed |