SCHEMBL189236

SCHEMBL189236

O=C(c1ccc(O)cc1)c1cccc(O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK1 P49759 1/20 0.75
DYRK1A Q13627 1/20 0.75
DYRK1B Q9Y463 1/20 0.75
FASN P49327 1/20 0.66
LMNA P02545 2/20 0.65
MAPT P10636 2/20 0.65
HTT P42858 2/20 0.65
ESR1 P03372 1/20 0.65
ESR2 Q92731 1/20 0.65
PKM P14618 1/20 0.65
HPGD P15428 1/20 0.65
HSD17B1 P14061 5/20 0.65
HSD17B2 P37059 5/20 0.65
MEN1 O00255 2/20 0.63
RAB9A P51151 2/20 0.63
KMT2A Q03164 2/20 0.63
NPC1 O15118 1/20 0.63
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27735439 1.00 CLK1 (0.75) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL22717015 0.96 MEN1 (0.70) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL8772372 0.94 LMNA (0.71) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL10395127 0.91 LMNA (0.71) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL698836 0.91 LMNA (0.71) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL29699163 0.91 FASN (0.76) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL809540 0.91 FASN (0.76) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL9131523 0.91 FASN (0.66) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL144795 0.89 ATM (0.74) CLK1DYRK1ADYRK1BFASNLMNA
SCHEMBL9229699 0.88 CA12 (0.73) CLK1DYRK1ADYRK1BFASNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2401249-B1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE DU PONT (US) 2013-05-15 EP claimed
US-8163864-B2 Sulfonated polyarylene compounds, membrane material made therefrom, method for the production thereof and use LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2012-04-24 US claimed
US-20110172317-A1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF AND USE LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2011-07-14 US claimed
US-20100217046-A1 PROCESS FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-26 US claimed
US-7772441-B1 Process for producing 3,4′ dihydroxybenzophenone E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-10 US claimed
EP-2046491-B1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE LEIBNIZ INST POLYMERFORSCHUNG (DE) 2010-05-12 EP claimed
US-7700680-B2 Aluminium hypophosphite (aluminium phosphinate) and linear polyester resins; good weatherability ITALMATCH CHEMICALS S.P.A. (IT) 2010-04-20 US claimed
JP-2009544831-A 2009-12-17 JP claimed
EP-2046491-A2 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE Leibniz-Institut für Polymerforschung Dresden e.V. (DE) 2009-04-15 EP claimed
US-20080090950-A1 Polyester Compositions Flame Retarded With Halogen-Free Additives ITALMATCH CHEMICALS (IT) 2008-04-17 US claimed
US-5288835-A 4,4*-bis(hydroxyphenoxy)biphenyl as one of the monomer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-22 US claimed
EP-0297525-B1 CATALYSIS OF ESTER INTERCHANGE REACTION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-20 EP claimed
EP-0148534-B1 BISMALEIMIDES AND PREPREG RESINS THEREFROM AMOCO CORPORATION (US) 1989-03-15 EP claimed
EP-0297525-A1 Catalysis of ester interchange reaction E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-01-04 EP claimed
US-4782131-A Ester interchange polyester preparation with alkali metal fluoride catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-01 US claimed
US-4600764-A P-HYDROXBENZOIC ACID, DIHYDROXBENZOPHENONE ISO-OR TEREPHTHALIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US claimed
EP-0148534-A1 Bismaleimides and prepreg resins therefrom AMOCO CORPORATION (US) 1985-07-17 EP claimed
EP-0026991-B1 AROMATIC POLYESTER AND FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-21 EP claimed
US-4269965-A COMPRISING MONOMERS OF P-HYDROXYBENZOIC ACID, 3,4'-DIHYDROXYBENZOPHENONE OR TEREPHTHALOYLDI(3-METHYL-4-HYDROXYBENZENE, AND TEREPHTHALIC ACID; LUSTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-26 US claimed
EP-0026991-A1 Aromatic polyester and filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-04-15 EP claimed