Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | TFEB | P19484 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469063 | 1.00 | MAPT (0.49) | MAPTNFE2L2PPARGCNR2CNR1 | |
| SCHEMBL9469148 | 0.86 | LMNA (0.53) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9469150 | 0.86 | LMNA (0.53) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9469663 | 0.86 | LMNA (0.53) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9470018 | 0.83 | PTGDR2 (0.49) | PPARALMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9470013 | 0.83 | PTGDR2 (0.49) | PPARALMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9470150 | 0.82 | LMNA (0.52) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9470154 | 0.82 | LMNA (0.52) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9469123 | 0.80 | MAPT (0.52) | MAPTPPARGCNR2CNR1PPARA | |
| SCHEMBL5318251 | 0.80 | LMNA (0.65) | MAPTPPARGCNR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |