Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469663 | 1.00 | LMNA (0.53) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL9469150 | 1.00 | LMNA (0.53) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL9470150 | 0.96 | LMNA (0.52) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL9470154 | 0.96 | LMNA (0.52) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL9469062 | 0.86 | MAPT (0.49) | LMNASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL2903656 | 0.86 | ALDH1A1 (0.57) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL9469063 | 0.86 | MAPT (0.49) | LMNASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL10741824 | 0.82 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL10740479 | 0.82 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTNPC1S1PR4 | |
| SCHEMBL10738850 | 0.82 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTNPC1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |