Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9469977 | 0.90 | SLC6A2 (0.52) | SLC6A2ATMALDH1A1TAAR1 | |
| Maleic Acid SCHEMBL9469974 | 0.90 | SLC6A2 (0.52) | SLC6A2ATMALDH1A1TAAR1 | |
| SCHEMBL3178412 | 0.84 | ATM (0.48) | TRIM24TRIM33ATMALDH1A1 | |
| SCHEMBL7611639 | 0.73 | SLC6A2 (0.50) | SLC6A2CTSD | |
| Hydrochloric Acid SCHEMBL7610830 | 0.71 | SLC6A2 (0.49) | SLC6A2CTSD | |
| SCHEMBL28802548 | 0.69 | ATM (0.69) | TRIM24TRIM33ATMALDH1A1 | |
| SCHEMBL8504874 | 0.66 | KCNH3 (0.40) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL31273663 | 0.66 | TRIM24 (0.48) | TRIM24TRIM33ATMALDH1A1 | |
| SCHEMBL28845024 | 0.66 | TRIM24 (0.44) | TRIM24TRIM33ATMALDH1A1 | |
| SCHEMBL9796154 | 0.66 | ATM (0.44) | TRIM24TRIM33ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792562-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-20 | — | — | US | claimed |
| US-5194618-A | Cognition activators for memory enhancers | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| US-5032599-A | Learning enhancement | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-4792562-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0226099-A2 | N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1987-06-24 | — | — | EP | disclosed |