Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | FABP3 | P05413 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728131 | 0.91 | LMNA (0.64) | RAB9ANPC1KDM4EALDH1A1FABP3 | |
| SCHEMBL452884 | 0.83 | KDM4E (0.53) | RAB9ANPC1KDM4EALDH1A1FABP3 | |
| SCHEMBL8149988 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8164009 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8157470 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8158463 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8162827 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8162521 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8148979 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 | |
| SCHEMBL8162369 | 0.81 | LMNA (0.61) | ALDH1A1FABP3LMNATSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | disclosed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | disclosed |