SCHEMBL452884

SCHEMBL452884

C=C(CCCOc1ccccc1Br)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
RAB9A P51151 5/20 0.50
NPC1 O15118 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 1/20 0.49
HTR7 P34969 1/20 0.45
LMNA P02545 3/20 0.44
GRM4 Q14833 1/20 0.43
FABP3 P05413 1/20 0.42
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520478 0.92 KDM4E (0.54) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL9469397 0.83 RAB9A (0.55) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL4836971 0.83 GAA (0.55) KDM4EALDH1A1KMT2ARAB9ANPC1
SCHEMBL3177108 0.83 THRA (0.38) KDM4EALDH1A1MEN1KMT2APOLB
SCHEMBL453710 0.82 HTR1B (0.52) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL819712 0.81 MEN1 (0.52) KDM4EALDH1A1MEN1KMT2ALMNA
SCHEMBL150208 0.80 TDP1 (0.38) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL450012 0.80 LMNA (0.58) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7918656 0.79 LIG1 (0.48) KDM4EALDH1A1MEN1KMT2ALMNA
SCHEMBL819675 0.79 KDM4E (0.56) KDM4EALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-8945439-B2 Method for manufacturing lens, apparatus for manufacturing lens, and method for manufacturing optical apparatus CANON KABUSHIKI KAISHA (JP) 2015-02-03 US disclosed
US-20120061864-A1 METHOD FOR MANUFACTURING LENS, APPARATUS FOR MANUFACTURING LENS, AND METHOD FOR MANUFACTURING OPTICAL APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed
US-7849022-B2 Optical functional sheet, and display device FUJIFILM CORPORATION (JP) 2010-12-07 US disclosed
US-20080013341-A1 OPTICAL FUNCTIONAL SHEET, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-01-17 US disclosed