Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200108 | 0.86 | ALDH1A1 (0.61) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9119583 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9120622 | 0.84 | ALDH1A1 (0.51) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9650805 | 0.84 | ALDH1A1 (0.51) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL14264211 | 0.82 | MAPT (0.44) | ALDH1A1GLASMN1; SMN2MAPTHTT | |
| SCHEMBL13482697 | 0.81 | MAPT (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL2183066 | 0.81 | MAPT (0.58) | ALDH1A1SMN1; SMN2MAPTKDM4EKMT2A | |
| SCHEMBL2557575 | 0.80 | L3MBTL1 (0.45) | ALDH1A1SMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL305728 | 0.80 | POLB (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL13941286 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GLASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254655-A | Made by hydrosilation of cyclic polysiloxanes and carbon-carbon bond-containing dye | HERCULES INCORPORATED (US) | 1993-10-19 | — | — | US | disclosed |