Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516623 | 0.79 | CFTR (0.50) | CFTRGOPCLMNACYP1A2CYP3A4 | |
| SCHEMBL5729305 | 0.69 | CFTR (1.00) | CFTRGOPCMAPTLMNAMAPK1 | |
| SCHEMBL10717574 | 0.67 | MAPT (0.42) | CFTRGOPCMAPTTP53LMNA | |
| SCHEMBL13783154 | 0.67 | CFTR (0.42) | CFTRGOPCLMNACYP1A2CYP3A4 | |
| SCHEMBL13782120 | 0.67 | CFTR (0.50) | CFTRGOPCCYP19A1CTRC | |
| SCHEMBL28176409 | 0.66 | MAPT (0.41) | CFTRGOPCMAPTTP53LMNA | |
| SCHEMBL11122355 | 0.64 | TSHR (0.40) | CFTRGOPCMAPTTP53LMNA | |
| SCHEMBL1673372 | 0.64 | ALDH1A1 (0.40) | CFTRGOPCALDH1A1MAOAMAOB | |
| SCHEMBL1673336 | 0.64 | ALDH1A1 (0.40) | CFTRGOPCALDH1A1MAOAMAOB | |
| SCHEMBL16857693 | 0.64 | ALDH1A1 (0.40) | CFTRGOPCALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243016-A | Improved solubility, polyimides, polyether ketones, polyesters, polyether sulfones | HAY ALLAN S (CA) | 1993-09-07 | — | — | US | disclosed |
| US-5182358-A | Polyetherketones, polyethersulfone, polyetherimides, solubility in organic solvents | HAY ALLAN S (CA) | 1993-01-26 | — | — | US | disclosed |