SCHEMBL28176409

SCHEMBL28176409

C=C1CC(c2ccccc2)C(=O)C1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
TP53 P04637 2/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2B P41595 1/20 0.41
CFTR P13569 1/20 0.41
GOPC Q9HD26 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 1/20 0.38
CTRC Q99895 1/20 0.38
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
SIGMAR1 Q99720 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29161356 0.81 DDB1 (0.46) MAPTTP53LMNACYP1A2CYP3A4
SCHEMBL3452689 0.79 TSHR (0.42) MAPTLMNACYP1A2CYP3A4CFTR
SCHEMBL2869249 0.78 ALDH1A1 (0.41) MAPTTP53CYP3A4MAPK1TSHR
SCHEMBL2867331 0.74 ALOX15 (0.43) MAPTTP53CYP3A4MAPK1TSHR
SCHEMBL15657030 0.69 KMT2A (0.52) MAPTTP53LMNACYP1A2CYP3A4
SCHEMBL11122355 0.68 TSHR (0.40) MAPTTP53LMNACYP1A2CYP3A4
SCHEMBL7234344 0.67 AKR1C3 (0.47) MAPTLMNACYP1A2CYP3A4CFTR
SCHEMBL9469689 0.66 CFTR (0.53) MAPTTP53LMNACYP1A2CYP3A4
SCHEMBL13838039 0.65 CTRC (0.45) MAPTCFTRGOPCTSHRKMT2A
SCHEMBL4971631 0.65 DDB1 (0.49) MAPTTP53LMNAMAPK1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107205894-A Cosmetic composition comprising synthetic phyllosilicates and polyols and/or UV filters 欧莱雅 2017-09-26 CN disclosed