Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707977 | 0.91 | AR (0.39) | LMNAARCYP2D6 | |
| SCHEMBL19470820 | 0.90 | KCNH2 (0.40) | KCNH2SLC9A1 | |
| SCHEMBL3110900 | 0.90 | KCNH2 (0.40) | KCNH2SLC9A1 | |
| SCHEMBL19470834 | 0.90 | KCNH2 (0.40) | KCNH2SLC9A1 | |
| SCHEMBL19470847 | 0.90 | KCNH2 (0.40) | KCNH2SLC9A1 | |
| SCHEMBL19356833 | 0.90 | KCNH2 (0.40) | KCNH2SLC9A1 | |
| SCHEMBL19470842 | 0.88 | LTA4H (0.38) | KCNH2LMNASLC9A1 | |
| SCHEMBL28827561 | 0.82 | MGLL (0.36) | LMNAARTP53CYP1A2CYP2D6 | |
| SCHEMBL28062922 | 0.82 | POLB (0.38) | KCNH2LMNAAR | |
| SCHEMBL702352 | 0.82 | ESR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229481-A | High-molecular weight, silicon-containing polymers and methods for the preparation and use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-07-20 | — | — | US | disclosed |