SCHEMBL9469830

SCHEMBL9469830

Nc1ccc(Cl)cc1-c1cc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.58
KDM4E B2RXH2 5/20 0.58
MAPT P10636 5/20 0.58
MEN1 O00255 4/20 0.58
ALDH1A1 P00352 4/20 0.58
KMT2A Q03164 4/20 0.58
NPC1 O15118 4/20 0.58
HPGD P15428 3/20 0.58
CASP3 P42574 2/20 0.58
SENP8 Q96LD8 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
KDR P35968 2/20 0.50
CHEK1 O14757 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.49
CYP19A1 P11511 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469591 0.87 RAB9A (0.58) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL29361867 0.81 KDR (0.58) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL221259 0.81 KDR (0.58) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL15942398 0.81 ESR1 (0.52) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL28763445 0.81 MEN1 (0.61) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL11477517 0.81 MAPT (0.68) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL11686705 0.80 MAPT (0.62) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL9469075 0.77 KDM4E (0.61) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL9469114 0.77 KDM4E (0.54) RAB9AKDM4EMAPTMEN1ALDH1A1
SCHEMBL5051826 0.74 KDR (0.68) RAB9AKDM4EMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999530-B2 Compounds and organic electronic device using same LG CHEM, LTD. (KR) 2015-04-07 US disclosed
US-8999530-B2 Compounds and organic electronic device using same LG CHEM, LTD. (KR) 2015-04-07 US disclosed
US-20140138659-A1 NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2014-05-22 US disclosed
US-20140138659-A1 NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2014-05-22 US disclosed
US-5214059-A Dermatitis, psoriasis HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1993-05-25 US disclosed
US-5166170-A 2-(AMINOARYL) INDOLES AND INDOLINES AS TOPICAL ANTIINFLAMMATORY AGENTS FOR THE TREATMENT OF SKIN DISORDERS HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-11-24 US disclosed
EP-0406734-A2 2-(Aminoaryl)indoles and indolines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-01-09 EP disclosed