Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361867 | 1.00 | KDR (0.58) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL3138805 | 0.87 | KDR (0.53) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL5051826 | 0.86 | KDR (0.68) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL2563486 | 0.84 | KDR (0.53) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL29733654 | 0.84 | KDR (0.53) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL29419326 | 0.84 | KDR (0.53) | KDRCHEK1RAB9AKDM4EMAPT | |
| Methane SCHEMBL28704887 | 0.84 | KDR (0.66) | KDRCHEK1RAB9AKDM4EMAPT | |
| Benzene SCHEMBL27629233 | 0.84 | RAB9A (0.69) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL8965829 | 0.82 | RAB9A (0.58) | KDRCHEK1RAB9AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3675763 | 0.82 | KDR (0.51) | KDRCHEK1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621220-B | Indolo [3,2-c ] quinoline compound and synthesis method thereof | 无锡学院 | 2023-07-04 | — | — | CN | claimed |
| CN-114621220-A | Indolo [3,2-c ] quinoline compound and synthetic method thereof | 无锡学院 | 2022-06-14 | — | — | CN | claimed |
| CN-108424416-B | Method for synthesizing indole [1,2-c ] quinazoline compound | 河南师范大学 | 2021-04-16 | — | — | CN | claimed |
| US-6656237-B1 | Fused polycyclic aromatic compound with exocyclic nitrogen group attached directly to a ring carbon; 1-amino naphthalene, 1,8-diaminonaphthalene, 5-aminoindole, 2-(2-aminophenyl) indole, 8-aminoquinoline | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-12-02 | — | — | US | claimed |
| EP-1137746-A1 | FUEL COMPOSITION WITH IMPROVED LUBRICITY PERFORMANCE | ExxonMobil Research and Engineering Company (US) | 2001-10-04 | — | — | EP | claimed |
| WO-2001021739-A1 | FUEL COMPOSITION WITH IMPROVED LUBRICITY PERFORMANCE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2001-03-29 | — | — | WO | claimed |
| US-20240124404-A1 | COMPOSITION FOR TREATING DISEASES RELATED TO ADVANCED GLYCATION END PRODUCTS COMPRISING INDOLE DERIVATIVE | METACEN THERAPEUTICS (KR) | 2024-04-18 | — | — | US | disclosed |
| EP-4353227-A1 | COMPOSITION INCLUDING INDOLE DERIVATIVE FOR PREVENTION OF ADVANCED GLYCATION END PRODUCT-RELATED DISEASE | Metacen Therapeutics (KR) | 2024-04-17 | — | — | EP | disclosed |
| CN-114621220-B | Indolo [3,2-c ] quinoline compound and synthesis method thereof | 无锡学院 | 2023-07-04 | — | — | CN | disclosed |
| CN-114621220-B | Indolo [3,2-c ] quinoline compound and synthesis method thereof | 无锡学院 | 2023-07-04 | — | — | CN | disclosed |
| US-11678576-B2 | Heterocyclic compound and organic light emitting element comprising same | LT MATERIALS CO., LTD. (KR) | 2023-06-13 | — | — | US | disclosed |
| CN-111253583-B | Dilatant hybrid dynamic polymer and dilatant realization method thereof | 厦门天策材料科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-114621220-A | Indolo [3,2-c ] quinoline compound and synthetic method thereof | 无锡学院 | 2022-06-14 | — | — | CN | disclosed |
| US-5214059-A | Dermatitis, psoriasis | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-05-25 | — | — | US | disclosed |
| US-5166170-A | 2-(AMINOARYL) INDOLES AND INDOLINES AS TOPICAL ANTIINFLAMMATORY AGENTS FOR THE TREATMENT OF SKIN DISORDERS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-24 | — | — | US | disclosed |
| US-5045539-A | 1H-indolo[3,2-c]quinoline-derivatives, compositions containing same, useful for treating pain, psychosis or convulsions | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-09-03 | — | — | US | disclosed |
| US-5006531-A | 5,6-dihydro(1H-indolo(3,2-C)quinoline-6,4'-piperidines) and related compounds which are useful for treating pain, psychosis or convulsions | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0407898-A1 | 5,6-dihydro(1H-indolo(3,2-c)quinoline-6,4-piperidines)and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-16 | — | — | EP | disclosed |
| EP-0406734-A2 | 2-(Aminoaryl)indoles and indolines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4057530-A | STABILIZERS FOR VINYL CHLORIDE POLYMERS | LABAZ (FR) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124404-A1 | COMPOSITION FOR TREATING DISEASES RELATED TO ADVANCED GLYCATION END PRODUCTS COMPRISING INDOLE DERIVATIVE | AGER, IDO1, IAPP | KDR 4006/4885CHEK1 3503/4885RAB9A 3408/4885 |
| US-11678576-B2 | Heterocyclic compound and organic light emitting element comprising same | CRY1, CRY2, CYP1A1 | KDR 2641/4885CHEK1 1843/4885RAB9A 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.