SCHEMBL9470229

SCHEMBL9470229

CC(=O)ON=C(Cl)c1ccc(Cl)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.51
RAB9A P51151 6/20 0.51
NPC1 O15118 5/20 0.51
HPGD P15428 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
CASP3 P42574 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 1/20 0.49
TSHR P16473 1/20 0.49
CASP1 P29466 1/20 0.49
GABRA1 P14867 3/20 0.46
GABRG2 P18507 3/20 0.46
GABRB3 P28472 3/20 0.46
GABRB2 P47870 2/20 0.46
ALDH1A1 P00352 3/20 0.45
PKM P14618 1/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699368 1.00 MAPT (0.51) MAPTRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL8204290 0.85 KMT2A (0.59) MAPTRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL11220483 0.80 RAB9A (0.49) MAPTRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL11220485 0.80 RAB9A (0.49) MAPTRAB9ANPC1HPGDSMN1; SMN2
Acetic Acid SCHEMBL9470199 0.77 MEN1 (0.61) MAPTRAB9ASMN1; SMN2L3MBTL1KMT2A
Acetic Acid SCHEMBL9470236 0.77 MEN1 (0.61) MAPTRAB9ASMN1; SMN2L3MBTL1KMT2A
SCHEMBL9471067 0.76 NPC1 (0.47) MAPTRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL11698620 0.76 NPC1 (0.47) MAPTRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL322161 0.73 TSHR (0.65) MAPTRAB9ASMN1; SMN2L3MBTL1KMT2A
SCHEMBL29384783 0.73 TSHR (0.65) MAPTRAB9ASMN1; SMN2L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5256693-A Synergistic mixture of alpha-chlorobenzaldoxime acetate and 2-bromo-2-nitro-1,3-diacetyloxypropane SOMAR CORPORATION (JP) 1993-10-26 US disclosed
EP-0524716-A1 Germicidal composition SOMAR CORPORATION (JP) 1993-01-27 EP disclosed
US-4018645-A Method of controlling slime during paper manufacture using alpha-chloro-acylbenzaldoxime derivatives SOMAR MANUFACTURING CO., LTD. (JA) 1977-04-19 US disclosed
US-3968240-A α-Chloro-o-acylbenzaldoxime derivatives as slime control agents SOMAR MANUFACTURING CO., LTD. (JA) 1976-07-06 US disclosed