SCHEMBL8204290

SCHEMBL8204290

CC(=O)ON=C(C)c1ccc(Cl)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
GAA P10253 1/20 0.55
MAPT P10636 9/20 0.52
RAB9A P51151 7/20 0.50
NPC1 O15118 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
HPGD P15428 4/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
CASP3 P42574 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
GABRA1 P14867 3/20 0.47
GABRG2 P18507 3/20 0.47
GABRB3 P28472 3/20 0.47
GABRB2 P47870 2/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9470229 0.85 MAPT (0.51) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL11699368 0.85 MAPT (0.51) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL6760769 0.81 KMT2A (0.65) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL6819513 0.81 KMT2A (0.65) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL10287190 0.79 RAB9A (0.52) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL11407263 0.78 GAA (0.53) KMT2AMEN1GAAMAPTRAB9A
Acetic Acid SCHEMBL8204291 0.76 KMT2A (0.86) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL8202608 0.75 LMNA (0.54) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL8809751 0.74 KMT2A (1.00) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL4306902 0.74 KMT2A (1.00) KMT2AMEN1GAAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8268976-A None JP disclosed
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed
EP-0735018-B1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL CO (JP) 1999-07-21 EP disclosed
US-5739401-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-14 US disclosed
JP-H08268976-A PRODUCTION OF 1-CHLORO-SUBSTITUTED PHENYLALKYLAMINE SUMITOMO CHEM CO LTD 1996-10-15 JP disclosed
EP-0735018-A1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed