SCHEMBL9470312

SCHEMBL9470312

CCCCCCCCCCCc1nnc(N)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
POLB P06746 4/20 0.80
GLS O94925 2/20 0.52
KDM4E B2RXH2 1/20 0.51
RAB9A P51151 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 1/20 0.47
ATM Q13315 1/20 0.46
DRD2 P14416 2/20 0.45
HRH2 P25021 2/20 0.45
HRH1 P35367 2/20 0.45
DRD3 P35462 2/20 0.45
HRH4 Q9H3N8 2/20 0.45
HRH3 Q9Y5N1 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ADRB2 P07550 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
ADRB1 P08588 1/20 0.43
HTR1A P08908 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11425081 1.00 ALDH1A1 (1.00) ALDH1A1POLBGLSKDM4ERAB9A
SCHEMBL23016888 1.00 ALDH1A1 (1.00) ALDH1A1POLBGLSKDM4ERAB9A
SCHEMBL28058879 1.00 ALDH1A1 (1.00) ALDH1A1POLBGLSKDM4ERAB9A
SCHEMBL11412602 0.98 ALDH1A1 (0.96) ALDH1A1POLBGLSKDM4ERAB9A
SCHEMBL1968819 0.94 ALDH1A1 (0.88) ALDH1A1POLBGLSKDM4ERAB9A
Hydrochloric Acid SCHEMBL20475888 0.92 ALDH1A1 (0.85) ALDH1A1POLBGLSKDM4ERAB9A
SCHEMBL14986945 0.89 ALDH1A1 (1.00) ALDH1A1POLBGLSL3MBTL1GAA
SCHEMBL15709879 0.89 ALDH1A1 (1.00) ALDH1A1POLBGLSL3MBTL1GAA
SCHEMBL14975757 0.87 ALDH1A1 (0.95) ALDH1A1POLBGLSL3MBTL1GAA
SCHEMBL22368217 0.85 ALDH1A1 (0.73) ALDH1A1POLBGLSRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399704-A Preparation method and application of long carbon chain thiadiazole CHANGZHOU HIGH-TECH RES INST OF NANJING UNIV 2016-03-16 CN disclosed
US-5185358-A Anticholesterol agents WARNER-LAMBERT CO. (US) 1993-02-09 US disclosed