Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179945 | 0.95 | KDM4E (0.55) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9179719 | 0.84 | MAPT (0.48) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9175188 | 0.84 | NNMT (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9470766 | 0.83 | KDM4E (0.41) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9471010 | 0.80 | XDH (0.44) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9178074 | 0.79 | KDM4E (0.44) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9471345 | 0.78 | MAPT (0.40) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9175444 | 0.77 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3949652 | 0.77 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3950860 | 0.77 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242912-A | Treatment of autoimmune and rheumatic diseases and osteoporosis | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0434844-A1 | NEW CYCLIC ANTHRANILIC ACID DERIVATIVE AND METHOD OF PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |