SCHEMBL9470686

SCHEMBL9470686

CC(=O)C(I)C(=O)Nc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.68
ALDH1A1 P00352 4/20 0.68
GAA P10253 2/20 0.68
ATM Q13315 2/20 0.68
LMNA P02545 1/20 0.68
HSD17B10 Q99714 2/20 0.55
NAPRT Q6XQN6 1/20 0.55
MME P08473 1/20 0.54
ACE P12821 1/20 0.54
POLB P06746 3/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
RXFP1 Q9HBX9 1/20 0.53
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
HSP90AA1 P07900 2/20 0.50
GPR55 Q9Y2T6 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.49
HPGD P15428 2/20 0.49
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2222178 0.81 MAPT (1.00) MAPTALDH1A1GAAATMLMNA
SCHEMBL935298 0.80 CYP1A2 (0.68) MAPTALDH1A1GAAATMLMNA
SCHEMBL20619928 0.80 ALDH1A1 (0.61) MAPTALDH1A1GAAATMLMNA
SCHEMBL4668132 0.78 ALDH1A1 (0.65) MAPTALDH1A1GAAATMLMNA
SCHEMBL6846422 0.77 MAPT (0.62) MAPTALDH1A1GAAATMLMNA
SCHEMBL11381083 0.77 MAPT (0.62) MAPTALDH1A1GAAATMLMNA
SCHEMBL11452160 0.77 CYP1A2 (0.64) MAPTALDH1A1GAAATMLMNA
SCHEMBL13246544 0.77 MAPT (0.62) MAPTALDH1A1GAAATMLMNA
SCHEMBL998876 0.76 MAPT (0.61) MAPTALDH1A1GAAATMLMNA
SCHEMBL23774829 0.76 MEN1 (0.60) MAPTALDH1A1GAAATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5266597-A Applying a fungicides EASTMAN KODAK COMPANY (US) 1993-11-30 US disclosed
US-5155136-A FUNGICIDAL, 2-ACYLACETANILIDE DERIVATIVES EASTMAN KODAK COMPANY (US) 1992-10-13 US disclosed