SCHEMBL947082

SCHEMBL947082

CCCCSCCNCCSCCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
CES1 P23141 1/20 0.35
CYP2C19 P33261 2/20 0.35
MEN1 O00255 1/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 1/20 0.35
ADH1B P00325 2/20 0.35
ADH1C P00326 2/20 0.35
ADH1A P07327 2/20 0.35
ADH7 P40394 2/20 0.35
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.34
CES2 O00748 1/20 0.33
CYP1A2 P05177 1/20 0.33
EPHX1 P07099 1/20 0.33
GMNN O75496 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679800 0.93 TSHR (0.62) TSHRALDH1A1LMNACYP2C19MEN1
SCHEMBL29306525 0.90 TSHR (0.55) TSHRALDH1A1MAPTLMNACES1
SCHEMBL31357726 0.90 TSHR (0.50) TSHRALDH1A1MAPTCES1ADH1B
SCHEMBL948108 0.90 TSHR (0.50) TSHRALDH1A1MAPTCES1ADH1B
SCHEMBL19627041 0.90 TSHR (0.50) TSHRALDH1A1MAPTCES1ADH1B
SCHEMBL7483245 0.90 TSHR (0.50) TSHRALDH1A1MAPTCES1ADH1B
SCHEMBL11464256 0.89 ALDH1A1 (0.39) TSHRALDH1A1MAPTLMNACES1
SCHEMBL11170853 0.86 TSHR (0.68) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL31575716 0.85 TSHR (0.46) TSHRALDH1A1MAPTCES1ADH1B
SCHEMBL26833379 0.84 TSHR (0.61) TSHRALDH1A1MAPTLMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456152-B1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST SASOL TECH PTY LTD (ZA) 2012-06-13 EP claimed
EP-1900735-B1 PYRIDAZINYL AMINE DERIVATIVES, THE USE THEREOF IN THE PREPARATION OF PICORNA VIRUS INHIBITORS INST PHARM & TOXICOLOGY AMMS (CN) 2012-06-13 EP claimed
JP-4308015-B2 2009-08-05 JP claimed
US-7300904-B2 Trimerisation and oligomerisation of olefins using a chromium based catalyst SASOL TECHNOLOGY (PTY) LTD. (ZA) 2007-11-27 US claimed
JP-2005533872-A 2005-11-10 JP claimed
US-20050131262-A1 Trimerisation and oligomerisation of olefins using a chromium based catalyst SASOL TECHNOLOGY (PTY) LTD. (ZA) 2005-06-16 US claimed
EP-1456152-A1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST Sasol Technology (Pty) Ltd (ZA) 2004-09-15 EP claimed
WO-2003053890-A1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST SASOL TECHNOLOGY (PTY) LTD (ZA) 2003-07-03 WO claimed
EP-2287143-B1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL CO LP (US) 2018-04-11 EP disclosed
EP-2287144-B1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL CO LP (US) 2018-04-11 EP disclosed
US-20170044275-A9 Methods of Preparation of an Olefin Oligomerization Catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-02-16 US disclosed
US-9550841-B2 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-01-24 US disclosed
US-20160251455-A1 Methods of Preparation of an Olefin Oligomerization Catalyst CHEVRON PHILLIPS CHEMICAL CO LP (US) 2016-09-01 US disclosed
EP-1716089-B1 METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL CO (US) 2015-04-08 EP disclosed
EP-1456152-A1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST Sasol Technology (Pty) Ltd (ZA) 2004-09-15 EP disclosed
WO-2003053890-A1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST SASOL TECHNOLOGY (PTY) LTD (ZA) 2003-07-03 WO disclosed
EP-0818512-B1 Quinoline derivative and use of same MITSUI CHEMICALS INC (JP) 2002-10-02 EP disclosed
US-6407242-B1 REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE MITSUI CHEMICALS, INC. (JP) 2002-06-18 US disclosed
US-6132640-A ZINC COMPLEXES OF QUINOLINE MITSUI CHEMICALS, INC. (JP) 2000-10-17 US disclosed
EP-0818512-A1 Quinoline derivative and use of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1998-01-14 EP disclosed