Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357726 | 1.00 | TSHR (0.50) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL19627041 | 1.00 | TSHR (0.50) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL7483245 | 1.00 | TSHR (0.50) | TSHRALDH1A1CES2THRBGMNN | |
| Hydrochloric Acid SCHEMBL31575716 | 0.95 | TSHR (0.46) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL10766453 | 0.91 | TSHR (0.50) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL947082 | 0.90 | TSHR (0.48) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL9426392 | 0.89 | CES2 (0.42) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL8023801 | 0.89 | CES2 (0.42) | TSHRALDH1A1CES2THRBGMNN | |
| SCHEMBL9679800 | 0.88 | TSHR (0.62) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL20714591 | 0.88 | FAAH (0.50) | GMNNPOLBMAPTCYP2C9BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456152-B1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECH PTY LTD (ZA) | 2012-06-13 | — | — | EP | claimed |
| JP-4308015-B2 | — | — | 2009-08-05 | — | — | JP | claimed |
| US-7300904-B2 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2007-11-27 | — | — | US | claimed |
| JP-2005533872-A | — | — | 2005-11-10 | — | — | JP | claimed |
| US-20050131262-A1 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2005-06-16 | — | — | US | claimed |
| EP-1456152-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | Sasol Technology (Pty) Ltd (ZA) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053890-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECHNOLOGY (PTY) LTD (ZA) | 2003-07-03 | — | — | WO | claimed |
| EP-2287144-B1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2287143-B1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-04-11 | — | — | EP | disclosed |
| US-20170044275-A9 | Methods of Preparation of an Olefin Oligomerization Catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-02-16 | — | — | US | disclosed |
| US-9550841-B2 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160251455-A1 | Methods of Preparation of an Olefin Oligomerization Catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2016-09-01 | — | — | US | disclosed |
| EP-1716089-B1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-04-08 | — | — | EP | disclosed |
| EP-1716089-A1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | Chevron Phillips Chemical Company LP (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082816-A1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187391-A1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-08-25 | — | — | US | disclosed |
| US-20050187098-A1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY, LP | 2005-08-25 | — | — | US | disclosed |
| US-20050131262-A1 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2005-06-16 | — | — | US | disclosed |
| EP-1456152-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | Sasol Technology (Pty) Ltd (ZA) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053890-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECHNOLOGY (PTY) LTD (ZA) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187391-A1 | Methods of preparation of an olefin oligomerization catalyst | ZRANB2, COG4, PPOX | TSHR 3138/4885ALDH1A1 4742/4885CES2 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.