Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309847 | 0.90 | TK1 (0.50) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL9308235 | 0.86 | TK1 (0.52) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL9310153 | 0.85 | TK1 (0.60) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL9311032 | 0.85 | TK1 (0.60) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL8797234 | 0.83 | TK1 (0.54) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL8689341 | 0.83 | TK1 (0.54) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL10516729 | 0.83 | TK1 (0.57) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL9471200 | 0.83 | TK1 (0.54) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL8536692 | 0.83 | TK1 (0.54) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL10514914 | 0.83 | TK1 (0.57) | ALDH1A1LMNAALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |