Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255972 | 0.83 | CYP3A4 (0.43) | KARS1HSD17B10ALOX15CYP3A4MAPT | |
| SCHEMBL29399820 | 0.83 | CYP3A4 (0.43) | KARS1HSD17B10ALOX15CYP3A4MAPT | |
| SCHEMBL151741 | 0.78 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL151743 | 0.78 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL151742 | 0.78 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL2603440 | 0.73 | KARS1 (0.47) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL9471891 | 0.73 | KARS1 (0.47) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL12547207 | 0.73 | KARS1 (0.47) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL15603521 | 0.70 | KARS1 (0.55) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL15603520 | 0.70 | KARS1 (0.55) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248696-A | Abietanoic acid derivatives | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1993-09-28 | — | — | US | claimed |
| WO-1992018119-A1 | COMPOSITION AND METHOD FOR TREATING TUMORS | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1992-10-29 | — | — | WO | claimed |
| US-5248696-A | Abietanoic acid derivatives | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1992018119-A1 | COMPOSITION AND METHOD FOR TREATING TUMORS | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1992-10-29 | — | — | WO | disclosed |