Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135198 | 0.84 | CA12 (0.49) | CA12CA9POLBKMT2AMEN1 | |
| SCHEMBL9156646 | 0.80 | ALDH1A1 (0.46) | CA12CA9POLBKMT2AMEN1 | |
| SCHEMBL10400233 | 0.77 | ALDH1A1 (0.73) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL9471237 | 0.76 | NPC1 (0.61) | CA12CA9POLBKMT2AMEN1 | |
| SCHEMBL9471179 | 0.76 | ALDH1A1 (0.51) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL9133481 | 0.75 | GLA (0.43) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7370201 | 0.74 | CACNA2D1 (0.65) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL401800 | 0.73 | GSK3B (0.57) | CA12CA9KMT2ANPC1KDM4E | |
| SCHEMBL2094701 | 0.73 | NPSR1 (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL9472002 | 0.73 | ALDH1A1 (0.60) | CA12CA9POLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223529-A | Nervous system and gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1993-06-29 | — | — | US | disclosed |