Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098360 | 0.79 | CA12 (0.66) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL135305 | 0.79 | CA12 (0.66) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL28764622 | 0.77 | ALDH1A1 (0.53) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL7999690 | 0.77 | ALDH1A1 (0.57) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL14594063 | 0.77 | KMT2A (0.60) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL10699963 | 0.76 | POLB (0.58) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL13812024 | 0.75 | ALDH1A1 (0.51) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL729028 | 0.75 | ALDH1A1 (0.60) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL1477933 | 0.74 | ALDH1A1 (0.57) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL133683 | 0.74 | KMT2A (0.59) | ALDH1A1POLBHSD17B10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223529-A | Nervous system and gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1993-06-29 | — | — | US | disclosed |