Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | GMNN | O75496 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498556 | 0.89 | CYP1A2 (0.38) | LMNASMN1; SMN2CYP1A2MAPK1GMNN | |
| SCHEMBL5467590 | 0.87 | SLC22A6 (0.38) | LMNASMN1; SMN2CYP1A2MAPK1TSHR | |
| SCHEMBL10904516 | 0.83 | SLC22A6 (0.35) | LMNASMN1; SMN2SLC22A6MMETDP1 | |
| SCHEMBL2223328 | 0.82 | CYP1A2 (0.42) | LMNACYP1A2MAPK1GMNNMAPT | |
| SCHEMBL15199823 | 0.82 | TSHR (0.35) | LMNASMN1; SMN2CYP1A2MAPK1GMNN | |
| Water SCHEMBL9651581 | 0.81 | SLC22A6 (0.33) | LMNASMN1; SMN2SLC22A6TDP1 | |
| SCHEMBL25825 | 0.80 | LMNA (0.38) | LMNASMN1; SMN2CYP1A2MAPK1GMNN | |
| SCHEMBL1118391 | 0.80 | MAPK1 (0.35) | LMNASMN1; SMN2MAPK1MMEACE | |
| SCHEMBL9472747 | 0.80 | TSHR (0.34) | TSHR | |
| SCHEMBL1441851 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264547-A | Optically active ether lactone, optically active polymer thereof, and process for producing the polymer | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5221755-A | Optically active ether lactone, optically active polymer thereof, and process for producing the polymer | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-06-22 | — | — | US | disclosed |