Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472785 | 0.86 | MAPK1 (0.63) | MAPK1ADORA3LMNAKMT2ANOD2 | |
| SCHEMBL9472732 | 0.85 | MAPK1 (0.46) | MAPK1ESR1PGRHTR1AADORA3 | |
| SCHEMBL9472943 | 0.83 | POLB (0.53) | MAPK1LMNAKMT2AMMP12ALDH1A1 | |
| SCHEMBL2336925 | 0.80 | MAPT (0.46) | MAPK1LMNAKMT2ATLR4ALDH1A1 | |
| SCHEMBL2336920 | 0.80 | MAPT (0.46) | MAPK1LMNAKMT2ATLR4ALDH1A1 | |
| SCHEMBL18169507 | 0.79 | MAPK1 (0.48) | MAPK1ESR1PGRHTR1AADORA3 | |
| SCHEMBL9472679 | 0.79 | TNF (0.41) | MAPK1ESR1PGRHTR1AADORA3 | |
| SCHEMBL4991663 | 0.79 | MAPK1 (0.50) | MAPK1TLR4ALDH1A1THRBAKT1 | |
| SCHEMBL4994069 | 0.79 | MAPK1 (0.50) | MAPK1TLR4ALDH1A1THRBAKT1 | |
| SCHEMBL14010283 | 0.79 | MAPK1 (0.50) | MAPK1TLR4ALDH1A1THRBAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264431-A | Inhibitors for proteinkinase C | CIBA-GEIGY CORP. (US) | 1993-11-23 | — | — | US | disclosed |