Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472679 | 0.94 | TNF (0.41) | MAPK1TNFKMT2ALMNAMEN1 | |
| SCHEMBL7781941 | 0.92 | KMT2A (0.44) | MAPK1TNFKMT2ALMNAMEN1 | |
| SCHEMBL9472943 | 0.87 | POLB (0.53) | MAPK1TNFKMT2ALMNAMEN1 | |
| SCHEMBL9472271 | 0.85 | MAPK1 (0.53) | MAPK1TNFKMT2ALMNAALDH1A1 | |
| SCHEMBL11170170 | 0.83 | MAPK1 (0.65) | MAPK1ALDH1A1POLB | |
| SCHEMBL9472639 | 0.81 | POLB (0.53) | MAPK1TNFKMT2ALMNAMEN1 | |
| SCHEMBL11170361 | 0.81 | MAPK1 (0.50) | MAPK1TNFKMT2ALMNATP53 | |
| SCHEMBL7226347 | 0.78 | LMNA (0.45) | MAPK1TNFKMT2ALMNAMEN1 | |
| SCHEMBL9472134 | 0.78 | MAPK1 (0.54) | MAPK1KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL7774705 | 0.76 | PTPN1 (0.45) | KMT2AMEN1ALDH1A1HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264431-A | Inhibitors for proteinkinase C | CIBA-GEIGY CORP. (US) | 1993-11-23 | — | — | US | disclosed |