Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991663 | 0.84 | MAPK1 (0.50) | MAPK1TLR4AKT1ALDH1A1THRB | |
| SCHEMBL4991659 | 0.84 | MAPK1 (0.50) | MAPK1TLR4AKT1ALDH1A1THRB | |
| SCHEMBL14010258 | 0.84 | MAPK1 (0.50) | MAPK1TLR4AKT1ALDH1A1THRB | |
| SCHEMBL14010283 | 0.84 | MAPK1 (0.50) | MAPK1TLR4AKT1ALDH1A1THRB | |
| SCHEMBL4994061 | 0.84 | MAPK1 (0.50) | MAPK1TLR4AKT1ALDH1A1THRB | |
| SCHEMBL4994069 | 0.84 | MAPK1 (0.50) | MAPK1TLR4AKT1ALDH1A1THRB | |
| SCHEMBL9472271 | 0.79 | MAPK1 (0.53) | MAPK1ESR1PGRHTR1AADORA3 | |
| SCHEMBL10598981 | 0.78 | MAPK1 (0.47) | MAPK1ESR1PGRHTR1AADORA3 | |
| SCHEMBL10379408 | 0.78 | NOD2 (0.45) | MAPK1ESR1PGRHTR1AADORA3 | |
| SCHEMBL61395 | 0.78 | MAPK1 (0.75) | MAPK1ESR1PGRHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210145975-A1 | IMMUNOGENIC COMPOUND | ALTIMMUNE UK LTD (GB) | 2021-05-20 | — | — | US | disclosed |
| US-10849984-B2 | Immunogenic compound | ALTIMMUNE UK LIMITED (GB) | 2020-12-01 | — | — | US | disclosed |
| US-20200038519-A1 | IMMUNOGENIC COMPOUND | ALTIMMUNE UK LIMITED | 2020-02-06 | — | — | US | disclosed |
| US-10434183-B2 | Immunogenic compound | Altimmune UK Ltd. (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20190125889-A1 | IMMUNOGENIC COMPOUND | ALTIMMUNE UK LIMITED (GB) | 2019-05-02 | — | — | US | disclosed |
| US-9962453-B2 | Immunogenic compound | ALTIMMUNE UK LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |
| US-20160310603-A1 | IMMUNOGENIC COMPOUND | ALTIMMUNE UK LIMITED (GB) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038519-A1 | IMMUNOGENIC COMPOUND | CD74, HLA-DRB1, MICA | MAPK1 2236/4885ESR1 4196/4885PGR 3617/4885 |
| US-10434183-B2 | Immunogenic compound | CD74, HLA-DRB1, MICA | MAPK1 2236/4885ESR1 4196/4885PGR 3617/4885 |
| US-20190125889-A1 | IMMUNOGENIC COMPOUND | CD74, HLA-DRB1, MICA | MAPK1 2236/4885ESR1 4196/4885PGR 3617/4885 |
| US-10849984-B2 | Immunogenic compound | CD74, HLA-DRB1, MICA | MAPK1 2236/4885ESR1 4196/4885PGR 3617/4885 |
| US-20210145975-A1 | IMMUNOGENIC COMPOUND | CD74, HLA-DRB1, MICA | MAPK1 2236/4885ESR1 4196/4885PGR 3617/4885 |
| US-20160310603-A1 | IMMUNOGENIC COMPOUND | CD74, HLA-DRB1, MICA | MAPK1 2236/4885ESR1 4196/4885PGR 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.