Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954097 | 0.87 | TP53 (0.43) | TP53 | |
| SCHEMBL8954053 | 0.86 | TP53 (0.46) | TP53 | |
| SCHEMBL8954114 | 0.85 | TP53 (0.47) | TP53 | |
| SCHEMBL8954062 | 0.85 | TP53 (0.47) | TP53 | |
| SCHEMBL8954029 | 0.85 | TP53 (0.46) | TP53 | |
| SCHEMBL8954170 | 0.83 | TP53 (0.46) | TP53 | |
| SCHEMBL8954116 | 0.83 | TP53 (0.43) | TP53 | |
| SCHEMBL7054174 | 0.83 | TP53 (0.48) | TP53 | |
| SCHEMBL8954122 | 0.82 | TP53 (0.48) | TP53 | |
| SCHEMBL8957028 | 0.82 | TP53 (0.45) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234917-A | Hypotensive agent, treatment of renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION | 1993-08-10 | — | — | US | disclosed |