Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060199 | 0.91 | TP53 (0.57) | TP53POLBALDH1A1GAAHSD17B10 | |
| SCHEMBL9272194 | 0.89 | TP53 (0.44) | TP53POLBHTTMAPK1 | |
| Hydrochloric Acid SCHEMBL8954138 | 0.88 | TP53 (0.43) | TP53POLBHTTMAPK1 | |
| SCHEMBL7059041 | 0.87 | TP53 (0.45) | TP53POLBALDH1A1GAAHSD17B10 | |
| SCHEMBL8954062 | 0.87 | TP53 (0.47) | TP53 | |
| Hydrochloric Acid SCHEMBL7060217 | 0.86 | TP53 (0.45) | TP53POLBALDH1A1GAAHSD17B10 | |
| SCHEMBL8954170 | 0.85 | TP53 (0.46) | TP53 | |
| SCHEMBL7054174 | 0.84 | TP53 (0.48) | TP53 | |
| SCHEMBL9472519 | 0.82 | TP53 (0.44) | TP53 | |
| SCHEMBL9472517 | 0.82 | ALDH1A1 (0.47) | TP53ALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530017-A | CONGESTIVE HEART FAILURE, RENAL FAILURE AND GLAUCOMA | SMITHKLINE BEECHAM CORP (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0701428-A1 | AGENTS CONTAINING 1,2-NAPTHOQUINONE FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 1996-03-20 | — | — | EP | disclosed |
| US-5444080-A | Hypotensive agents | SMITHKLINE BEECHAM CORPORATION (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1994028862-A1 | AGENTS CONTAINING 1,2-NAPTHOQUINONE FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | disclosed |
| EP-0541705-A4 | SUBSTITUTED 1H-IMIDAZOL-5-YL)ALKANOIC ACIDS | — | 1993-11-10 | — | — | EP | disclosed |
| EP-0541705-A1 | SUBSTITUTED 1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0437103-A2 | Substituted 5-(alkyl)carboxamide imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-17 | — | — | EP | disclosed |