Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473749 | 0.86 | POLB (0.65) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL6867867 | 0.82 | LMNA (0.62) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL6859193 | 0.82 | LMNA (0.62) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL8722653 | 0.81 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL8722654 | 0.81 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL23742930 | 0.81 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL10359936 | 0.81 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL15514610 | 0.81 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL24086073 | 0.81 | LMNA (0.55) | CYP2D6ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL9472221 | 0.80 | POLB (0.66) | CYP2D6ALDH1A1MAPK1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264431-A | Inhibitors for proteinkinase C | CIBA-GEIGY CORP. (US) | 1993-11-23 | — | — | US | disclosed |