Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474180 | 0.88 | EPHX1 (0.49) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL4389938 | 0.79 | TRPM8 (0.52) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL29243148 | 0.78 | EPHX1 (0.46) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL29029157 | 0.78 | EPHX1 (0.43) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL30604482 | 0.76 | TRPM8 (0.62) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL30524155 | 0.75 | EPHX1 (0.50) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL10028628 | 0.75 | EPHX1 (0.50) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL9951715 | 0.74 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL3274993 | 0.74 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL1030886 | 0.74 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266592-A | Ketals | HAARMANN & REIMER GMBH (DE) | 1993-11-30 | — | — | US | disclosed |