Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581260 | 0.93 | HMGCR (0.44) | HMGCRVCAM1CNR1CNR2GAA | |
| SCHEMBL10572623 | 0.92 | HMGCR (0.35) | HMGCRHIF1ATP53CYP2C9CYP2C19 | |
| SCHEMBL8093478 | 0.86 | HMGCR (0.37) | HMGCRVCAM1CNR1CNR2GAA | |
| SCHEMBL224342 | 0.84 | HMGCR (0.38) | HMGCRVCAM1CNR1CNR2GAA | |
| SCHEMBL10312311 | 0.84 | HMGCR (0.38) | HMGCRVCAM1CNR1CNR2GAA | |
| SCHEMBL581163 | 0.83 | HMGCR (0.45) | HMGCRGAAKMT2AATMNPSR1 | |
| SCHEMBL870709 | 0.83 | HMGCR (0.45) | HMGCRGAAKMT2AATMNPSR1 | |
| SCHEMBL9431129 | 0.83 | HMGCR (0.45) | HMGCRVCAM1CNR1CNR2GAA | |
| SCHEMBL28046935 | 0.80 | GAA (0.38) | HMGCRVCAM1GAAALDH1A1TSHR | |
| SCHEMBL27827539 | 0.78 | HMGCR (0.34) | HMGCRVCAM1CNR1CNR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244953-A | Polymers, oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |