Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MYOC | Q99972 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434657 | 0.86 | KMT2A (0.84) | KMT2AMAPTRAB9AHTTPKM | |
| SCHEMBL8572381 | 0.86 | KMT2A (0.83) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10636579 | 0.86 | KMT2A (0.84) | KMT2AMAPTRAB9AHTTPKM | |
| SCHEMBL4951809 | 0.86 | KMT2A (0.84) | KMT2AMAPTRAB9AHTTPKM | |
| SCHEMBL9134339 | 0.86 | KMT2A (0.83) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23898948 | 0.86 | KMT2A (0.83) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL542043 | 0.86 | KMT2A (0.84) | KMT2AMAPTRAB9AHTTPKM | |
| SCHEMBL8274340 | 0.85 | KMT2A (0.81) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7872779 | 0.85 | KMT2A (0.81) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL237695 | 0.85 | KMT2A (0.64) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237034-A | Preparation of siloxane modified polyimide resin | CHEIL SYNTHETICS, INC. (KR) | 1993-08-17 | — | — | US | disclosed |