Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.81 |
| ▸ | MEN1 | O00255 | 7/20 | 0.81 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | MITF | O75030 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274340 | 1.00 | KMT2A (0.81) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL8572381 | 0.89 | KMT2A (0.83) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL23898948 | 0.89 | KMT2A (0.83) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL9134339 | 0.89 | KMT2A (0.83) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL306161 | 0.87 | POLB (0.81) | KMT2AMEN1HTTPOLBMAPK1 | |
| SCHEMBL2061754 | 0.87 | ALOX5 (0.77) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL2633343 | 0.87 | ALOX5 (0.77) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL9644607 | 0.86 | LMNA (0.73) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL9799705 | 0.86 | MEN1 (0.74) | KMT2AMEN1MAPTRAB9ANPC1 | |
| Iodide SCHEMBL22235392 | 0.85 | POLB (0.78) | KMT2AMEN1HTTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187285-B1 | IN PARTICULAR MAGNETIC RESONANCE IMAGING (MRI) FOR MAGNETIC CATIONS. | GUERBET (FR) | 2001-02-13 | — | — | US | disclosed |