Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524545 | 0.85 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9641763 | 0.84 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9641781 | 0.82 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL9475050 | 0.82 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9474906 | 0.82 | ALOX5 (0.91) | ALOX5 | |
| SCHEMBL8933773 | 0.81 | ALOX5 (1.00) | ALOX5 | |
| Ammonia Solution, Strong SCHEMBL9473339 | 0.80 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL9474724 | 0.80 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL9475019 | 0.80 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL27823569 | 0.79 | ALOX5 (0.50) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0292699-A2 | Urea based lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-11-30 | — | — | EP | disclosed |