Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633909 | 0.94 | SYK (0.44) | SYKRAD52MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7512302 | 0.84 | RAD52 (0.56) | SYKRAD52MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11615704 | 0.79 | RAB9A (0.49) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8629687 | 0.79 | POLB (0.50) | MAPTALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL16628855 | 0.79 | MAPK1 (0.54) | MAPTL3MBTL1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3125469 | 0.78 | CA12 (0.56) | SYKRAD52MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1152315 | 0.78 | MAPT (0.57) | MAPTL3MBTL1ALDH1A1ALOX12MEN1 | |
| SCHEMBL1151631 | 0.77 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11583731 | 0.77 | MAPT (0.71) | MAPTL3MBTL1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11364527 | 0.77 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243047-A | Triazole/thiazole amino-s-triazine bonding agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-07 | — | — | US | disclosed |
| US-4978756-A | A 2-MERCAPTO, ALKYLANOYL, ALKENOYL OR ALKDIENOYL AMINO BENZOTHIOZOLE; METALS PROTECTIVE COATING; IMPROVED BONDING OF METALS AND RUBBER; TIRE CORDS | ICI AMERICAS INC. (US) | 1990-12-18 | — | — | US | disclosed |