Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | TXN | P10599 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475009 | 0.94 | SYK (0.47) | SYKRAD52IKBKBALDH1A1CYP3A4 | |
| SCHEMBL7512302 | 0.80 | RAD52 (0.56) | SYKRAD52ALDH1A1CYP3A4TP53 | |
| SCHEMBL22214935 | 0.78 | TXN (0.69) | SYKTXNMAPTVCPCA12 | |
| SCHEMBL6301188 | 0.75 | MAPT (0.67) | SYKRAD52ALDH1A1CYP3A4TP53 | |
| SCHEMBL351125 | 0.75 | MAPT (0.67) | SYKRAD52ALDH1A1CYP3A4TP53 | |
| SCHEMBL9518383 | 0.75 | MAPT (0.67) | SYKRAD52ALDH1A1CYP3A4TP53 | |
| SCHEMBL16628855 | 0.75 | MAPK1 (0.54) | IKBKBALDH1A1CYP3A4TP53TDP1 | |
| SCHEMBL8629687 | 0.75 | POLB (0.50) | TXNALDH1A1TP53MAPTALOX12 | |
| SCHEMBL11615704 | 0.75 | RAB9A (0.49) | ALDH1A1CYP3A4MAPTHTTCYP1A2 | |
| SCHEMBL1152315 | 0.74 | MAPT (0.57) | IKBKBALDH1A1TP53TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508390-B1 | Light-sensitive silver halide photographic material | KONISHIROKU PHOTO IND (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5258280-A | 2-amino-4,6-dimercapto-1,3,5-triazine derivatives; blackness, high covering power | KONICA CORPORATION (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0508390-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |