Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295376 | 0.86 | TP53 (0.63) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL8507480 | 0.81 | TP53 (0.50) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL6454000 | 0.77 | TP53 (0.46) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL16705054 | 0.76 | TP53 (0.77) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL8507478 | 0.76 | TP53 (0.44) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL7601778 | 0.73 | TP53 (0.35) | TP53ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7601412 | 0.70 | ALDH1A1 (0.44) | TP53ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL60489 | 0.69 | GABRA1 (0.50) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL27542653 | 0.69 | NR1I2 (0.60) | TP53TDP1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL11795501 | 0.68 | TP53 (0.75) | TP53TDP1ALDH1A1NR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217522-A | HERBICIDAL SULPHONYLGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |