SCHEMBL9475220

SCHEMBL9475220

CCC(C)c1ccc(C(C)N(O)C(N)=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 16/20 0.69
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9474417 0.81 ALOX5 (1.00) ALOX5
SCHEMBL9774492 0.80 ALOX5 (0.68) ALOX5
SCHEMBL9473434 0.80 ALOX5 (0.71) ALOX5
SCHEMBL9473244 0.80 ALOX5 (0.71) ALOX5
SCHEMBL9373793 0.80 ALOX5 (1.00) ALOX5
SCHEMBL13524545 0.79 ALOX5 (1.00) ALOX5
SCHEMBL9443901 0.79 ALOX5 (1.00) ALOX5TSHR
SCHEMBL9475225 0.79 ALOX5 (0.66) ALOX5ALDH1A1
SCHEMBL9473684 0.78 ALOX5 (0.65) ALOX5
SCHEMBL9474906 0.77 ALOX5 (0.91) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5185363-A Administering for treatment of inflammatory diseases ABBOTT LABORATORIES (US) 1993-02-09 US disclosed