SCHEMBL9475225

SCHEMBL9475225

CCCCc1ccc(C(C)N(O)C(N)=O)cc1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 11/20 0.66
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9473741 0.83 ALOX5 (0.73) ALOX5
SCHEMBL9774409 0.80 ALOX5 (0.70) ALOX5
SCHEMBL9443901 0.80 ALOX5 (1.00) ALOX5
SCHEMBL9475220 0.79 ALOX5 (0.69) ALOX5ALDH1A1
SCHEMBL9474417 0.75 ALOX5 (1.00) ALOX5
SCHEMBL28842675 0.74 ALDH1A1 (0.51) ALDH1A1HPGDHSD17B10
SCHEMBL6803238 0.74 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10
SCHEMBL9774492 0.74 ALOX5 (0.68) ALOX5
SCHEMBL9473434 0.74 ALOX5 (0.71) ALOX5
SCHEMBL9473244 0.74 ALOX5 (0.71) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5185363-A Administering for treatment of inflammatory diseases ABBOTT LABORATORIES (US) 1993-02-09 US disclosed