SCHEMBL9475239

SCHEMBL9475239

CN(C)c1ccccc1C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.43
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
HTR6 P50406 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CHEK1 O14757 1/20 0.36
NEK2 P51955 1/20 0.36
LIMK1 P53667 1/20 0.36
DYRK1A Q13627 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
MEN1 O00255 1/20 0.35
TTR P02766 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6135294 0.82 KCNN4 (0.39) KCNN4CRHBPCRHR2MEN1KMT2A
SCHEMBL6556714 0.79 KCNN4 (0.61) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL5799085 0.76 KCNN4 (0.42) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL28565820 0.75 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP2C19
SCHEMBL65263 0.75 MAPT (0.55) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL11100244 0.75 CRHBP (0.39) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL29987688 0.75 ALDH1A1 (0.46) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL1201242 0.75 ALDH1A1 (0.46) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL27787980 0.74 KCNN4 (0.35) KCNN4MAPTALDH1A1GAASMN1; SMN2
SCHEMBL1768874 0.73 ACP1 (0.46) MAPTALDH1A1GAASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213927-A Multilayer; electroconductive, charge transport and charge generating layer EASTMAN KODAK COMPANY (US) 1993-05-25 US claimed