Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.51 |
| ▸ | GCGR | P47871 | 2/20 | 0.51 |
| ▸ | RAF1 | P04049 | 4/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071183 | 0.79 | NOX1 (1.00) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11054293 | 0.78 | NOX1 (0.72) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL8113912 | 0.78 | KMT2A (0.62) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5074753 | 0.76 | MAPK13 (0.83) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL16667652 | 0.74 | MAPK13 (0.83) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| Benzene SCHEMBL28852698 | 0.74 | MAPK13 (0.82) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL104130 | 0.74 | MAPK13 (0.82) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4551697 | 0.74 | NOX1 (0.72) | NOX1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL14149523 | 0.73 | MAPT (0.53) | MAPTGAAHPGDALOX5 | |
| SCHEMBL94910 | 0.72 | NPC1 (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5117241-A | — | — | None | — | — | JP | disclosed |
| JP-H05117241-A | 4-HYDROPEROXY-2-(N,N-DISUBSTITUTED AMINOPHENYL)-4,5-DIPHENYL-4H-ISOIMIDAZOLE | ICHIKAWA TETSUYA | 1993-05-14 | — | — | JP | disclosed |