SCHEMBL1071183

SCHEMBL1071183

CN(C)c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 1/20 1.00
ALOX5 P09917 2/20 0.67
MAPK13 O15264 9/20 0.65
MAPK12 P53778 9/20 0.65
MAPK11 Q15759 9/20 0.65
MAPK14 Q16539 9/20 0.65
GCGR P47871 4/20 0.65
RAF1 P04049 4/20 0.63
MAPK9 P45984 1/20 0.62
KDM4E B2RXH2 2/20 0.59
ALDH1A1 P00352 2/20 0.59
GLA P06280 2/20 0.59
GAA P10253 2/20 0.59
HPGD P15428 2/20 0.59
KMT2A Q03164 2/20 0.59
TP53 P04637 4/20 0.57
MAPT P10636 4/20 0.57
BRAF P15056 1/20 0.57
MEN1 O00255 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14336058 0.88 NOX1 (0.78) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL12152229 0.87 NOX1 (0.76) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL5074753 0.87 MAPK13 (0.83) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL5622957 0.86 ALOX5 (0.87) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL6468252 0.86 NOX1 (0.76) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL8032578 0.86 NOX1 (0.76) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL12555646 0.86 NOX1 (0.74) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL31742329 0.85 RAF1 (0.76) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL30762099 0.85 RAF1 (0.76) NOX1ALOX5MAPK13MAPK12MAPK11
SCHEMBL1170149 0.85 NOX1 (0.73) NOX1ALOX5MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206718-A Core-shell material and preparation method thereof 华为技术有限公司 2024-06-18 CN claimed
US-9969878-B2 Polyalkylene carbonate resin composition having high thermal stability SK INNOVATION CO., LTD. (KR) 2018-05-15 US claimed
US-9777153-B2 Polyalkylene carbonate resin composition having an interpenetrating crosslinked structure SK INNOVATION CO., LTD. (KR) 2017-10-03 US claimed
EP-2845878-B1 POLYALKYLENE CARBONATE RESIN COMPOSITION HAVING AN INTERPENETRATING CROSSLINKED STRUCTURE SK INNOVATION CO LTD (KR) 2017-07-12 EP claimed
CN-103865035-B Use the composition epoxy resin of solvation solid 气体产品与化学公司 2017-06-30 CN claimed
US-20160122535-A1 Polyalkylene Carbonate Resin Composition Having High Thermal Stability SK INNOVATION CO, LTD. (KR) 2016-05-05 US claimed
US-9309381-B2 Epoxy resin compositions using solvated solids AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-04-12 US claimed
US-20150099829-A1 Polyalkylene Carbonate Resin Composition Having an Interpenetrating Crosslinked Structure SK INNOVATION CO, LTD. (KR) 2015-04-09 US claimed
EP-2845878-A2 POLYALKYLENE CARBONATE RESIN COMPOSITION HAVING AN INTERPENETRATING CROSSLINKED STRUCTURE SK Innovation Co., Ltd. (KR) 2015-03-11 EP claimed
US-20140264822-A1 THERMOSETTING RESIN COMPOSITIONS WITH LOW COEFFICIENT OF THERMAL EXPANSION HENKEL CORPORATION (US) 2014-09-18 US claimed
US-20020128353-A1 Fluxing underfill compositions LOCTITE CORPORATION 2002-09-12 US claimed
WO-2002070191-A1 FLUXING UNDERFILL COMPOSITIONS HENKEL LOCTITE CORPORATION (US) 2002-09-12 WO claimed
US-20020058778-A1 Toughened thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-05-16 US claimed
US-20020058756-A1 Underfill sealants with improved adhesion, improved resistance to moisture absorption and improved resistance to stress cracking LOCTITE CORPORATION 2002-05-16 US claimed
US-6342577-B1 Thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-01-29 US claimed
WO-2001083607-A1 RHEOLOGY-CONTROLLED EPOXY-BASED COMPOSITIONS HENKEL LOCTITE CORPORATION (US) 2001-11-08 WO claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO claimed
EP-1090057-A1 REWORKABLE THERMOSETTING RESIN COMPOSITIONS LOCTITE CORPORATION (US) 2001-04-11 EP claimed
WO-2000079582-A9 CONTROLLABLY DEGRADABLE COMPOSITION OF HETEROATOM CARBOCYCLIC OR EPOXY RESIN AND CURING AGENT LOCTITE CORP (US) 2001-03-15 WO claimed
WO-2000056799-A1 REWORKABLE THERMOSETTING RESIN COMPOSITIONS LOCTITE CORPORATION (US) 2000-09-28 WO claimed